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Compazine prochlorperazine is an prescription-strength antiemetic and antipsychotic approved for the treatment of severe nausea and vomiting, schizophrenia, and generalized non-psychotic anxiety. However, it is not used for migraine or headache prevention and is rarely given as a prescription for these conditions on a regular, long-term basis. Prochlorperazine is recommended for medication rebound or overuse headaches, intractable headaches, status migrainosus, and for headaches and migraines in which severe nausea and vomiting are the predominant symptoms. It is also considered among the most effective medications for severe childhood migraines, with and without nausea. Compazine is not an opioid, https://www.sciencedirect.com and it is not addictive.
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Analyses of seventeen placebo-controlled trials modal duration of 10 weeks, largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1. Over the course of a typical week controlled trial, the rate of death in drugtreated patients was about 4. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular e. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic s of the patients is not clear.
Take Compazine exactly as prescribed by your doctor. This medicine is also used to treat schizophrenia. Nausea and vomiting; nausea and vomiting caused by cancer drugs; prevent nausea and vomiting from cancer chemotherapy.
Edeltraud (taken for 2 to 6 years) 04.01.2019
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Prochlorperazine is also used to control severe nausea and vomiting. You should not use prochlorperazine if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications.
Jakob (taken for 2 to 6 years) 23.10.2018
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IM: mg administered hours before induction of anesthesia; may be repeated once 30 minutes after initial dose. Lower initial dose and adjust gradually; 2. Restlessness immediate restlessness or agitation may be treated with diphenhydramine 25 mg IV push.
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Label It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting. A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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