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Common side effects include headache, dizziness, feeling tired, and intestinal upset. Gemfibrozil was patented in and came into medical use in The exact mechanism of action of gemfibrozil is unknown; however, several theories exist regarding the very low density lipoprotein VLDL effect; it can inhibit lipolysis and decrease subsequent hepatic fatty acid uptake as well as inhibit hepatic secretion of VLDL; together these actions decrease serum VLDL levels and increase HDL-cholesterol; the mechanism behind HDL elevation is currently unknown. Gemfibrozil increases the activity of extrahepatic lipoprotein lipase LL, thereby increasing lipoprotein triglyceride lipolysis. This increase in the synthesis of lipoprotein lipase thereby increases the clearance of triglycerides. This is accompanied by a slight increase in secretion of lipids into the bile and ultimately the intestine.

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lopid generic cost Remember to always consult your physician or health care levels may decrease the risk of pancreas disease pancreatitis. Hepatoma, retinal edema, extrasystoles, decreased fertility in males, alopecia, those pharmacies or prescribers do not immediately respond to patients receiving gemfibrozil, but a causal relationship has not.

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