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The article by Meyer et al. Given the potential for coexisting lactic acidosis and diabetic ketoacidosis, how can one justify its use? A modest average reduction of daily insulin requirements, 4. Furthermore, it is likely that the incidence of hypoglycemia would be much greater if more aggressive metabolic targets of HbA 1c had been applied. It appears that these prescriptions were given because of a failure to identify latent autoimmune diabetes in adults or because the physician believed that the potential for insulin dose reduction and lipid improvement justified a putative small risk for diabetic ketoacidosis and lactic acidosis. Indeed, the diagnosis of metabolic syndrome can frequently be made in the type 1 diabetic population. The results of the study by Meyer et al. Questions about long-term safety and efficacy in this patient population remain unanswered.

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Use: To improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise. Use: To improve glycemic control in children with type 2 diabetes mellitus as an adjunct to diet and exercise.

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DOI: Background: Extract of leaves from the Stevia rebaudiana Bertoni have been used in the traditional treatment of diabetes in Paraguay and Brazil. These glycosides have many potential benefits in the management of the complications of diabetes. The treatment of type 2 diabetes mellitus T2DM is currently unsatisfactory. Therefore, we investigated the possible effects of stevia on treatment of T2DM when concurrently given with common antidiabetic agents in a trial to provide a safe and effective therapeutic antidiabetic combination.

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