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Generic norvasc cost

December 25, 2018


Amlodipine is used alone or in combination with other classes of antihypertensive agents in the management of hypertension. Amlodipine in fixed combination with atorvastatin Caduet is used in patients for whom treatment with both amlodipine and atorvastatin is appropriate. Ultimately, choice of antihypertensive therapy should be individualized, considering the clinical characteristics of the patient e. Because many patients eventually will need drugs from 2 or more antihypertensive classes, experts generally state that the emphasis should be placed on achieving appropriate blood pressure control rather than on identifying a preferred drug to achieve that control. In the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial ALLHAT study, the long-term cardiovascular morbidity and mortality benefit of a long-acting dihydropyridine calcium-channel blocker amlodipine, a thiazide-like diuretic chlorthalidone, and an ACE inhibitor lisinopril were compared in a broad population of patients with hypertension at risk for coronary heart disease. Although these antihypertensive agents were comparably effective in providing important cardiovascular benefit, apparent differences in certain secondary outcomes were observed. Patients receiving the ACE inhibitor experienced higher risks of stroke, combined cardiovascular disease, GI bleeding, and angioedema, while those receiving the calcium-channel blocker were at higher risk of developing heart failure.

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Common side effects include swelling, feeling tired, abdominal pain, and nausea. Amlodipine was patented in, and approved for medical use in Amlodipine is used in the management of hypertension and coronary artery disease in people with either stable angina where chest pain occurs mostly after physical or emotional stress or vasospastic angina where it occurs in cycles and without heart failure. It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease. Amlodipine can be administered to adults and children 6—17 years of age.

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