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What is metoclopramide, and how does it work. Metoclopramide is a prokinetic drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. In patients with gastroesophageal reflux disease GERD, a weakened lower esophageal sphincter allows reflux https://www.adam.com of stomach acid into the esophagus, causing heartburn and damage to the esophagus esophagitis. Metoclopramide decreases the reflux of stomach acid by strengthening the muscle of the lower esophageal sphincter. Metoclopramide also stimulates the muscles of the stomach and thereby hastens emptying of solid and liquid meals from the stomach and into the intestines.

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Inclusive of all Taxes. This medication is a gastrointestinal stimulant and antinauseant, prescribed for heartburn and esophagitis due to GERD and for treating patients who have gastroparesis partial paralysis of the stomach and prevention of nausea and vomiting associated with cancer chemotherapy. Metoclopramide helps the stomach get rid of food and lowers signs of an upset stomach, throwing up, heartburn, and fullness. It is usually taken 4 times a day on an empty stomach, 30 minutes before each meal and at bedtime. Injection is administered by health care providers into the vein.

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