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Provera contains medroxyprogesterone acetate, a derivative of progesterone, as its active ingredient. It is a white to off-white, odorless crystalline powder that is stable in air and that melts between ? C and ? Hypersensitivity to MPA or to any component of Provera eg lactose monohydrate, maize starch, sucrose, liquid paraffin, talc and calcium stearate. Some reports suggest under certain circumstances, an association between intrauterine exposure to progestational drugs in the first trimester of pregnancy and genital abnormalities in fetuses. If the patient becomes pregnant while using this drug, the patient should be apprised of the potential hazard to the fetus.

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Medroxyprogesterone is used to treat conditions such as absent or irregular menstrual periods, or abnormal uterine bleeding. Medroxyprogesterone is also used to decrease the risk of endometrial hyperplasia a condition that may lead to uterine cancer while taking estrogens. Medroxyprogesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Medroxyprogesterone should not be used to prevent heart disease, stroke, or dementia. This medicine may actually increase your risk of developing these conditions. Long-term use of medroxyprogesterone may increase your risk of breast cancer, heart attack, stroke, or blood clot.

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Your dose of medroxyprogesterone will depend on what you are being treated for. Your doctor or pharmacist will tell you how many tablets to take and how often to take them.


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