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In the case of Arimidex, or any Type-I inhibitor, it works by binding to the substrate the aromatase enzyme thus rendering it inactive and therefore unable to convert testosterone into estrogen. In clinical use, drugs in this class are used to halt the progression of Breast Cancer in women, as well as for a preventative measure in women who are in a high risk group. In our little world of illicit steroid use, athletics and bodybuilding, it is used as an ancillary compound on a cycle containing steroids which aromatize undergo a specific metabolic shift into estrogen. That dose may be slightly excessive, however. In a study conducted on males, examining estrogen suppression in males caused by Arimidex, both.
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